منابع مشابه
Immunosuppressive drugs and fertility
Immunosuppressive drugs are used in the treatment of inflammatory and autoimmune diseases, as well as in transplantation. Frequently prescribed in young people, these treatments may have deleterious effects on fertility, pregnancy outcomes and the unborn child. This review aims to summarize the main gonadal side effects of immunosuppressants, to detail the effects on fertility and pregnancy of ...
متن کاملOral immunosuppressive drugs.
The last few decades have witnessed remarkable achievements in the development of immunosuppressive drugs, made possible by significant advances in molecular immunology and improved understanding of the mechanisms by which cells communicate. The identification of the relevant cells involved in a pathological process is the key to understanding effective immunosuppressive strategies. For example...
متن کاملImmunosuppressive Drugs and Kidney Post-transplant Diabetes Mellitus
Background: As the rate of renal transplantation increases, more immunosuppressive drugs such as cyclosporine A (CsA) are consumed, particularly during the early months following transplantation, leading to post-transplant diabetes mellitus (PTDM) which can cause death. Objective: The present study examined the role of CsA in causing PTDM and other effect...
متن کاملPharmacodynamic monitoring of immunosuppressive drugs.
Pharmacodynamic (PD) monitoring measures the biological response to a drug, which alone--or coupled with pharmacokinetics--provides a novel method for optimization of drug dosing. PD monitoring has been investigated by us and other investigators primarily for four immunosuppressive drugs: cyclosporine (CsA), azathioprine (AZA), mycophenolate mofetil (MMF), and rapamycin (RAPA). PD monitoring of...
متن کاملNewer immunosuppressive drugs: a review.
In recent years, many new immunosuppressive drugs have been discovered and developed for clinical use in transplantation. This review focuses on those drugs (leflunomide, mycophenolate mofetil, sirolimus, tacrolimus) that have been shown to have immunosuppressive activity in patients. Different anti-interleukin-2 receptor antibodies are also reviewed as an example of a resurgence of development...
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ژورنال
عنوان ژورنال: Australian Prescriber
سال: 2009
ISSN: 0312-8008,1839-3942
DOI: 10.18773/austprescr.2009.037